The delayed stress response is mediated by which hormone?

The delayed stress response is mediated by which hormone?

• A. Adrenaline
• B. Cortisol
• C. Insulin
• D. Endorphins

Answer: (B)

The delayed stress response is driven by cortisol. When stress is present, the hypothalamus activates the HPA axis, prompting the pituitary to release ACTH, which then signals the adrenal cortex to release cortisol. Cortisol sustains energy by increasing glucose availability, helps mobilize fats, and modulates immune and inflammatory responses, keeping the body equipped to handle stress over hours or days. This slower, longer-lasting action contrasts with adrenaline, which produces rapid, short-term fight-or-flight effects. Insulin regulates blood sugar rather than coordinating a stress-specific response, and endorphins mainly affect pain and mood rather than the hormonal stress cascade.

The delayed stress response is driven by cortisol. When stress is present, the hypothalamus activates the HPA axis, prompting the pituitary to release ACTH, which then signals the adrenal cortex to release cortisol. Cortisol sustains energy by increasing glucose availability, helps mobilize fats, and modulates immune and inflammatory responses, keeping the body equipped to handle stress over hours or days. This slower, longer-lasting action contrasts with adrenaline, which produces rapid, short-term fight-or-flight effects. Insulin regulates blood sugar rather than coordinating a stress-specific response, and endorphins mainly affect pain and mood rather than the hormonal stress cascade.